Reaction systems represent a theoretical framework based on the regulation mechanisms of facilitation and inhibition of biochemical reactions. The dynamic...
Publications
popFBA: tackling intratumour heterogeneity with Flux Balance Analysis ...
MOTIVATION: Intratumour heterogeneity poses many challenges to the treatment of cancer. Unfortunately, the transcriptional and metabolic information retrieved by currently...
Detection of cAMP and of PKA activity in Saccharomyces cerevisiae sing...
In Saccharomyces cerevisiae the second messenger cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) play a central role in...
Whi5 phosphorylation embedded in the G1/S network dynamically controls...
In budding yeast, overcoming of a critical size to enter S phase and the mitosis/mating switch--two central cell fate events--take...